So what have I learned about using this amazing new cancer drug, Neoplasene?
Well, there may be surviving cancer cells after the initial application of Neoplasene. This can happen when the medication does not come into contact with all of the mass due to its size or shape. A series of applications may be necessary and would be determined by the needs of each individual case.
There are three treatment options with Neoplasene – topical, injectible, and oral. Any combination of these forms may be used on a patient. And occasionally removal by surgery, or debulking, prior to beginning any Neoplasene treatment may be the optimal approach.
Topical treatment with the ointment form works well for exterior or surface cancers. The mass can be treated all at once, or in sections, depending on various factors. Topical application of the ointment will create a local effect and cause a slight burning sensation on cancerous tissue. Successfully treating with topical Neoplasene depends upon getting a sufficient amount of the drug in contact with the cancerous tissue long enough to trigger apoptosis. This may mean close monitoring, bandaging or using the dreaded E-collar to prevent licking and chewing by the patient. A small price to pay for the wonderful work of the drug.
The injectible form is called NeoplaseneX. It is administered directly into the tumor and can provide the concentration needed to eliminate a mass when it isn’t possible to remove it in other ways. Even though it is applied directly into a mass there is also a generalized effect. This means tumor tissue at distant sites anywhere in the body will also start to die. This reaction must be monitored well.
Giving Neoplasene orally, as a capsule or liquid also has a generalized effect, like the injectible. Cancer cells anywhere in the body will respond with apoptosis. Oral treatment can be used alone, but is usually used as long term continued care in conjunction with initial treatment by injection or topical. It requires a long term commitment by the family for its success. Oral Neoplasene is a somewhat bitter liquid that is usually well accepted when mixed with wet foods, esp. those with in a sauce or gravy. For the very finicky palate the liquid can be put into a capsule. This must be immediately prior to administration as it will start to dissolve the capsule within minutes.
When oral Neoplasene is given, care must be taken to avoid digestive upset. It is best given with a meal. This creates an immediate dilution in the stomach. Once diluted in the circulatory system, it is able to do its work without causing harm to healthy cells. The optimal dosage of the oral form is “to gastric tolerance.” This means that a moderate dosage is initiated and then the dose is increased slowly until the first sign of gastric upset occurs. The maintenance dose for long term aftercare is then set just below this amount for maximal effect with no side effects. The length of this treatment will vary from case to case.
In my next post I'll talk about what else can be expected during treatment.
Wednesday, November 21, 2007
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3 comments:
I am using oral Neoplasene on my 10 year old Leonberger, Jazzie. She has metastasized cancer--a tumor in each lung. She has stopped coughing and until today, she has been behaving like a puppy. For some reason, she started the day by vomiting though she did eat this morning after receiving Reglan. She gets Reglan prior to each dose. We will re-xray next week to see if the tumors have shrunk. Without Neoplasene, we really have little hope of prolonging her life. I would love to hear from anyone who is using oral Neoplasene. Dr. Fox has been extremely helpful but it's nice to be in touch with other folks using the same treatment option.
As a follow up to my last posting on Jazzie, she had been treated with amoxicillin for a bladder infection and panacur for giardia which is probably what caused the stomach upset. She vomited and aspirated. It took 2 weeks for a full recovery but she's back eating as if starved and is on her Neoplasene again. We had no choice but to treat the other conditions--I should have taken her off the Neoplasene for a week while treating the bladder but now she's okay. I'm keeping her on cranberry to avoid future infections. Jazzie is walking (albiet slowly) over a mile a day, resting when she wants. With this breed, exercise feeds their souls so we try to keep her life as normal as possible. I recommend Neoplasene to anyone with a pet who is fighting cancer.
Hi,
My 13 year old cat has an adenosarcoma in the lung. Surgery doesn't seem to be an option so he's
on supplements, chinese herbs, a homeopathic regimen from Dr. Loops and oral Neoplasene. Thank god he's eating it with his food
though he's only been on it for 5 days and he's not at the therapeutic dosage level. I'd be very graateful to hear about others experience with
neoplasene with aggressive lung tumors. Thanks!!!!
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Dr. Yasson is unable to diagnose specific cases through her blog, but comments about her posts are always welcome! If you would like to discuss your specific case please contact us at info@holvet.net and we will be happy to help.